CD146 (DGR12926) Rabbit mAb (PBS Only)
Product Name :
CD146 (DGR12926) Rabbit mAb (PBS Only)
Cat.No.:
db11170-PBS
Synonyms :
CD146; MUC18
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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Immunogen
A synthetic peptide of human CD146
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Gene ID
4162
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Swiss Prot
P43121
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Synonyms
CD146; MUC18
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:500
ICC/IF: 1:100-1:200
FC: 1:20-1:100
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Calculated MW
72 kDa
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Observed MW
120 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR12926
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of CD146 in C6,Hela cell lysates using
db11170(1:1000 diluted).
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Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using
db11170
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.