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CD146 (DGR12926) Rabbit mAb (PBS Only)
db11170-PBS
Datasheet

Product Name : CD146 (DGR12926) Rabbit mAb (PBS Only)

Cat.No.: db11170-PBS

Synonyms : CD146; MUC18

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
  • Immunogen A synthetic peptide of human CD146
  • Gene ID 4162
  • Swiss Prot P43121
  • Synonyms CD146; MUC18
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, ICC/IF, FC
  • Recommended dilution WB: 1:1000
    IHC-P: 1:200-1:500
    ICC/IF: 1:100-1:200
    FC: 1:20-1:100
  • Calculated MW 72 kDa
  • Observed MW 120 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR12926
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/ml
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot detection of CD146 in C6,Hela cell lysates using db11170(1:1000 diluted).
  • Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using db11170
订购信息
  • Package Price (RMB)
  • 100μg 5798
  • 货期:现货
For research use only. Not intended for diagnostic.