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Phospho-eIF4E (Ser209) (DGR19212) Rabbit mAb (PBS Only)
db11218-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E
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Gene ID
1977
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Swiss Prot
P06730
- Synonyms CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, IP
- Calculated MW 25 kDa
- Observed MW 25 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR19212
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of eIF4E (Phospho-Ser209) in K562,Rat Brain,C6,3T3 cell lysates using eIF4E (Phospho-Ser209) antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human lung cancer using db11218 antibody. -
Immunofluorescent analysis of HeLa cells using db11218 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
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For research use only. Not intended for diagnostic.
