Noxa (DGR18795) Rabbit mAb (PBS Only)
Product Name :
Noxa (DGR18795) Rabbit mAb (PBS Only)
Cat.No.:
db11258-PBS
Synonyms :
APR; NOXA
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
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Immunogen
A synthetic peptide of human Noxa
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Gene ID
5366
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Swiss Prot
Q13794
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Synonyms
APR; NOXA
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000-1:5000
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Calculated MW
6 kDa
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Observed MW
10 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR18795
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of Noxa in Hela,A549,HL-60,U251 cell lysates using Noxa antibody(1:1000 diluted).
订购信息
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Package
Price (RMB)
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100μg
4498
- 货期:现货
For research use only. Not intended for diagnostic.