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Phospho-MSK1 (Ser360) (DGR11224) Rabbit mAb (PBS Only)
db11273-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression.
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser360 of human MSK1
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Gene ID
9252
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Swiss Prot
O75582
- Synonyms MSK1; RLPK; MSPK1
- Reactivity Human,Mouse,Rat
- Application WB, ICC/IF
- Calculated MW 90 kDa
- Observed MW 90 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11224
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of Phospho-MSK1 (Ser360) in C6,CHO-K1 cell lysates using Phospho-MSK1 (Ser360) antibody(1:1000 diluted). -
Immunofluorescent analysis of HeLa cells using db11273 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 100μg 7858
- 货期：现货
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For research use only. Not intended for diagnostic.
