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BMAL1 (DGR34336) Rabbit mAb
db11283
Datasheet
- Background The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021]
- Immunogen A synthetic peptide of human BMAL1
-
Gene ID
406
11865
29657
-
Swiss Prot
O00327
Q9WTL8
Q9EPW1
- Synonyms TIC; JAP3; MOP3; ARNTL; PASD3; ARNTL1; BMAL1c; bHLHe5
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, IP
-
Recommended dilution
WB: 1:1000
IHC: 1:200-1:1000
ICC/IF: 1:100
IP: 1:20-1:40 - Calculated MW 69 kDa
- Observed MW 78 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR34336
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Rat brain tissue using db11283 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
