EGFR单克隆抗体(DGR32135) | 高特异性&高亲和力

产品中心 Products Center

您当前的位置：

Recombinant DGRmAb^®

Phospho-EGFR (Tyr1173) (DGR32135) Rabbit mAb (PBS Only)

db11285-PBS

Datasheet

Product Name : Phospho-EGFR (Tyr1173) (DGR32135) Rabbit mAb (PBS Only)

Cat.No.: db11285-PBS

Synonyms : ERBB; HER1; mENA; ERBB1; PIG61; NISBD2

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jun 2020]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr1173 of human EGFR
Gene ID 1956
Swiss Prot P00533
Synonyms ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Reactivity Human
Application WB, ICC/IF, FC
Recommended dilution WB: 1:1000
ICC/IF: 1:20-1:50
FC: 1:20-1:50
Calculated MW 134 kDa
Observed MW 175 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR32135
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of EGFR (phospho-Tyr1173) in Hela,A549 cell lysates using db11285(1:1000 diluted).
Immunofluorescent analysis of HeLa cells using db11285

订购信息