Dynactin p150Glued (DGR34335) Rabbit mAb
Product Name :
Dynactin p150Glued (DGR34335) Rabbit mAb
Cat.No.:
db11301
Synonyms :
P135; DP-150; DAP-150
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008]
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Immunogen
A synthetic peptide of human Dynactin p150Glued
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Gene ID
1639
13191
29167
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Swiss Prot
Q14203
O08788
P28023
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Synonyms
P135; DP-150; DAP-150
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Reactivity
Human,Mouse,Rat
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Application
WB, IP
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Recommended dilution
WB: 1:1000
IP: 1:20-1:50
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Calculated MW
142 kDa
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Observed MW
150 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR34335
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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