DEPDC5单克隆抗体(DGR34000) | 高特异性&高亲和力

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Recombinant DGRmAb^®

DEPDC5 (DGR34000) Rabbit mAb (PBS Only)

db11303-PBS

Datasheet

Product Name : DEPDC5 (DGR34000) Rabbit mAb (PBS Only)

Cat.No.: db11303-PBS

Synonyms : DEP.5; FFEVF; FPEVF; FFEVF1

Application：

Reactivity : Human, Mouse

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Immunogen A synthetic peptide of human DEPDC5
Gene ID 9681
277854
Swiss Prot O75140
P61460
Synonyms DEP.5; FFEVF; FPEVF; FFEVF1
Reactivity Human,Mouse
Application WB
Recommended dilution WB: 1:1000
Calculated MW 181 kDa
Observed MW 181 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR34000
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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