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Conjugation/Formulation：Un-conjugated
- Background This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Immunogen A synthetic peptide of human DAB2
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Gene ID
1601
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Swiss Prot
P98082
- Synonyms DOC2; DOC-2
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:500
IP: 1:20-1:50 - Calculated MW 83 kDa
- Observed MW 96 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR21087
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of DAB2 in HepG2,U2OS,U251 using DAB2 antibody(1:1000 diluted) -
Immunohistochemical analysis of paraffin-embedded human lung cancer using db11306 antibody.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
