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Conjugation/Formulation：Un-conjugated
- Background The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
- Immunogen A synthetic peptide of human EIF2S1
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Gene ID
1965
13665
54318
-
Swiss Prot
P05198
Q6ZWX6
P68101
- Synonyms EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:500-1:2000
IP: 1:20-1:50 - Calculated MW 36 kDa
- Observed MW 36 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR34204
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from MCF-7，HepG2 cells using db11308 at 1:1000. -
Western blot analysis of extracts from T24 cells and Rat spleen tissue using db11308 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
