GAD1, GAD2单克隆抗体(DGR20516) | 高特异性&高亲和力

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Recombinant DGRmAb^®

GAD1/2 (DGR20516) Rabbit mAb (PBS Only)

db11316-PBS

Datasheet

Product Name : GAD1/2 (DGR20516) Rabbit mAb (PBS Only)

Cat.No.: db11316-PBS

Synonyms : GAD; SCP; CPSQ1

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human GAD1
Gene ID 2571
2572
Swiss Prot Q05329
Q99259
Synonyms GAD; SCP; CPSQ1
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, IP
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:1000
ICC/IF: 1:100
IP: 1:20-1:50
Calculated MW 65,67 kDa
Observed MW 65,67 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20516
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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