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Conjugation/Formulation：Un-conjugated
- Background This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]
- Immunogen Recombinant protein of human UHRF1
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Gene ID
29128
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Swiss Prot
Q96T88
- Synonyms Np95; hNP95; ICBP90; RNF106; TDRD22; hUHRF1; huNp95
- Reactivity Human
- Application WB, IHC-P, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:100
ICC/IF: 1:200-1:500
FC: 1:50-1:100
IP: 1:20-1:50 - Calculated MW 89 kDa
- Observed MW 97 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR11715
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of UHRF1 in K562,Hela cell lysates using UHRF1 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
