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ALIX (DGR14864) Rabbit mAb (PBS Only)
db11331-PBS
Datasheet
Product Name : ALIX (DGR14864) Rabbit mAb (PBS Only)
Cat.No.: db11331-PBS
Synonyms : AIP1; ALIX; HP95; DRIP4
Application：
Reactivity : Human
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
- Immunogen Recombinant protein of human ALIX
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Gene ID
10015
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Swiss Prot
Q8WUM4
- Synonyms AIP1; ALIX; HP95; DRIP4
- Reactivity Human
- Application WB
- Recommended dilution WB: 1:1000-1:5000
- Calculated MW 96 kDa
- Observed MW 96 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14864
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HT-1080 cells using db11331 at 1:1000.
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
