MICA/B (DGR19290) Rabbit mAb
Product Name :
MICA/B (DGR19290) Rabbit mAb
Cat.No.:
db11355
Synonyms :
MIC-A; PERB11.1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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Immunogen
Recombinant protein of human MICA
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Gene ID
100507436
4277
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Swiss Prot
Q29980
Q29983
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Synonyms
MIC-A; PERB11.1
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Reactivity
Human
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Application
WB, IP
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Recommended dilution
WB: 1:1000
IP: 1:20-1:50
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Calculated MW
43 kDa
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Observed MW
60-75 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR19290
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from HeLa cells using db11355 at 1:1000.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.