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MMP2 (DGR12980) Rabbit mAb (PBS Only)
db11372-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
- Immunogen A synthetic peptide of human MMP2
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Gene ID
4313
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Swiss Prot
P08253
- Synonyms CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II
- Reactivity Human,Mouse,Rat
- Application WB, ICC/IF, FC
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Recommended dilution
WB: 1:1000-1:5000
ICC/IF: 1:100-1:200
FC: 1:200-1:500 - Calculated MW 74 kDa
- Observed MW 72,64 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR12980
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of MMP2 in mouse lung,mouse heart cell lysates using MMP2 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
