p53 单克隆抗体(DGR13712) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Acetyl-p53 (Lys305) (DGR13712) Rabbit mAb (PBS Only)

db11373-PBS

Datasheet

Product Name : Acetyl-p53 (Lys305) (DGR13712) Rabbit mAb (PBS Only)

Cat.No.: db11373-PBS

Synonyms : P53; BCC7; LFS1; TRP53

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Immunogen A synthetic acetylpeptide corresponding to residues surrounding Lys305 of human p53
Gene ID 7157
22059
24842
Swiss Prot P04637
P02340
P10361
Synonyms P53; BCC7; LFS1; TRP53
Reactivity Human,Mouse,Rat
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 44 kDa
Observed MW 53 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR13712
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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