Phospho-PDGFR beta (Tyr751) (DGR16422) Rabbit mAb
Product Name :
Phospho-PDGFR beta (Tyr751) (DGR16422) Rabbit mAb
Cat.No.:
db11388
Synonyms :
IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr751 of human PDGFR beta
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Gene ID
5159
18596
24629
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Swiss Prot
P09619
P05622
Q05030
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Synonyms
IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1
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Reactivity
Human,Mouse,Rat
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
124 kDa
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Observed MW
190 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR16422
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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