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CCR7 (DGR32787) Rabbit mAb

Product Name : CCR7 (DGR32787) Rabbit mAb

Cat.No.: db11393

Synonyms : BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
  • Immunogen A synthetic peptide of human CCR7
  • Gene ID 1236
  • Swiss Prot P32248
  • Synonyms BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, ICC/IF, IP
  • Recommended dilution WB: 1:2000-1:10000
    IHC-P: 1:100
    ICC/IF: 1:100
    IP: 1:20
  • Calculated MW 43 kDa
  • Observed MW 43 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR32787
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of CCR7 in Rat Brain,C6,3T3,Hela cell lysates using CCR7 antibody(1:1000 diluted).
  • Western blot analysis of extracts from Rat spleen,Mouse spleen tissue using db11393 at 1:2000.
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.