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Phospho-PKC alpha (Thr497) (DGR34855) Rabbit mAb (PBS Only)
db11402-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr497 of human PKC alpha
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Gene ID
5578
18750
24680
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Swiss Prot
P17252
P20444
P05696
- Synonyms AAG6; PKCA; PRKACA; PKC-alpha
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P
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Recommended dilution
WB: 1:5000-1:50000
IHC-P: 1:1000-1:10000 - Calculated MW 77 kDa
- Observed MW 77 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR34855
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Rat heart tissue using db11402
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
