Daxx (DGR31549) Rabbit mAb (PBS Only)
Product Name :
Daxx (DGR31549) Rabbit mAb (PBS Only)
Cat.No.:
db11451-PBS
Synonyms :
DAP6; EAP1; BING2; SMIM40
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
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Immunogen
A synthetic peptide of human Daxx
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Gene ID
1616
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Swiss Prot
Q9UER7
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Synonyms
DAP6; EAP1; BING2; SMIM40
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, ICC/IF, FC
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Calculated MW
81 kDa
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Observed MW
110 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR31549
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of Daxx in HepG2,U251,HL-60 using Daxx antibody(1:1000 diluted).
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Western blot analysis of extracts from HCT116 cells using
db11451 at 1:2000.
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Immunofluorescent analysis of K562 cells using
db11451 antibody (green), and DAPI (blue).
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.