DDIT3单克隆抗体(DGR14242) | 高特异性&高亲和力

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Recombinant DGRmAb^®

DDIT3 (DGR14242) Rabbit mAb (PBS Only)

db11608-PBS

Datasheet

Product Name : DDIT3 (DGR14242) Rabbit mAb (PBS Only)

Cat.No.: db11608-PBS

Synonyms : CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; C/EBPzeta

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
Immunogen A synthetic peptide of human DDIT3
Gene ID 1649
Swiss Prot P35638
Synonyms CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; C/EBPzeta
Reactivity Human,Mouse,Rat
Application WB, IHC-P
Calculated MW 19 kDa
Observed MW 27 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR14242
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/mL
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of DDIT3 in K562,CHO-K1,Hela cell lysates using DDIT3 antibody(1:1000 diluted).
Western blot analysis of extracts from HepG2，HCT116 cells using db11608 at 1:1000.
Immunohistochemical analysis of paraffin-embedded human breast cancer using db11608 antibody.

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