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IKB alpha (DGR14519) Rabbit mAb (PBS Only)
db11682-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
- Immunogen A synthetic peptide of human IKB alpha
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Gene ID
4792
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Swiss Prot
P25963
- Synonyms IKBA; MAD-3; NFKBI
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC, IP
- Calculated MW 36 kDa
- Observed MW 39 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14519
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from 3T3, HeLa cells using db11682 at 1:1000. -
Immunohistochemical analysis of paraffin-embedded human tonsil using db11682 antibody. -
Western blot analysis of extracts from C6 cells using db11682 at 1:1000. -
Immunofluorescence analysis of HeLa cells labelling IKB alpha with db11682.
The cells were fixed with cold 100% methanol (10min, 4℃) and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db11682 (1:50) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)-AF488 db10005, shown in green). Nuclear DNA was labeled in blue with DAPI.
Control: Secondary antibody only.
订购信息
- Package Price (RMB)
- 100μg 7858
- 货期：现货
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For research use only. Not intended for diagnostic.
