TLR5单克隆抗体(DGR34922) | 高特异性&高亲和力

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Recombinant DGRmAb^®

TLR5 (DGR34922) Rabbit mAb (PBS Only)

db11708-PBS

Datasheet

Product Name : TLR5 (DGR34922) Rabbit mAb (PBS Only)

Cat.No.: db11708-PBS

Synonyms : SLE1; TIL3; SLEB1; MELIOS

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
Immunogen Recombinant protein of human TLR5
Gene ID 7100
Swiss Prot O60602
Synonyms SLE1; TIL3; SLEB1; MELIOS
Reactivity Human,Mouse,Rat
Application WB
Calculated MW 98 kDa
Observed MW 98 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR34922
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/mL
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot analysis of extracts from Rat spleen tissue and A549, THP-1 cells using db11708 at 1:1000.

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