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Macro H2A.1 (DGR14657) Rabbit mAb

Product Name : Macro H2A.1 (DGR14657) Rabbit mAb

Cat.No.: db11728

Synonyms : H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
  • Immunogen A synthetic peptide of human macroH2A.1
  • Gene ID 9555
  • Swiss Prot O75367
  • Synonyms H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, ICC/IF
  • Recommended dilution WB: 1:2000-1:20000
    IHC-P: 1:50-1:100
    ICC/IF: 1:200-1:500
  • Calculated MW 40 kDa
  • Observed MW 40 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR14657
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of macroH2A.1 in Rat Brain,C6,3T3 cell lysates using macroH2A.1 antibody(1:1000 diluted).
  • Immunofluorescent analysis of HeLa cells using db11728 antibody (green), and DAPI (blue).
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.