Macro H2A.1 (DGR14657) Rabbit mAb
Product Name :
Macro H2A.1 (DGR14657) Rabbit mAb
Cat.No.:
db11728
Synonyms :
H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
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Immunogen
A synthetic peptide of human macroH2A.1
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Gene ID
9555
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Swiss Prot
O75367
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Synonyms
H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
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Reactivity
Human,Mouse,Rat
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Application
WB, IHC-P, ICC/IF
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Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:50-1:100
ICC/IF: 1:200-1:500
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Calculated MW
40 kDa
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Observed MW
40 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14657
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot detection of macroH2A.1 in Rat Brain,C6,3T3 cell lysates using macroH2A.1 antibody(1:1000 diluted).
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Immunofluorescent analysis of HeLa cells using db11728 antibody (green), and DAPI (blue).
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.