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ATP citrate lyase (DGR14757) Rabbit mAb (PBS Only)
db11738-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
- Immunogen A synthetic peptide of human ATP citrate lyase
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Gene ID
47
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Swiss Prot
P53396
- Synonyms ACL; ATPCL; CLATP
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, FC, IP
- Calculated MW 121 kDa
- Observed MW 121 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14757
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of ATP citrate lyase in K562,C6,3T3,Hela cell lysates using ATP citrate lyase antibody(1:1000 diluted). -
Immunofluorescent analysis of A549 cells using db11738 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
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For research use only. Not intended for diagnostic.
