Product Name : XIAP (DGR16638) Rabbit mAb (PBS Only)
Cat.No.: db11787-PBS
Synonyms : API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
Reactivity : Human, Mouse, Rat
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
- Immunogen Recombinant protein of human XIAP
-
Gene ID
331
-
Swiss Prot
Q60989
- Synonyms API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
- Reactivity Human,Mouse,Rat
- Application WB
- Calculated MW 57 kDa
- Observed MW 53 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16638
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
-
Western blot detection of XIAP in K562,Rat Brain,3T3 cell lysates using db11787(1:1000 diluted).
- Package Price (RMB)
- 100μg 5798
- 货期：现货
