FAK单克隆抗体(DGR15314) | 高特异性&高亲和力

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Recombinant DGRmAb^®

FAK (DGR15314) Rabbit mAb (PBS Only)

db11806-PBS

Datasheet

Product Name : FAK (DGR15314) Rabbit mAb (PBS Only)

Cat.No.: db11806-PBS

Synonyms : FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
Immunogen A synthetic peptide of human FAK
Gene ID 5747
Swiss Prot Q05397
Synonyms FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
Reactivity Human,Mouse,Rat
Application WB, IHC-P
Recommended dilution WB: 1:1000
IHC-P: 1:100-1:200
Calculated MW 119 kDa
Observed MW 125 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR15314
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of FAK in K562,C6,3T3,Hela cell lysates using db11806(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using db11806

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