TAK1单克隆抗体(DGR20443) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Phospho-TAK1 (Ser439) (DGR20443) Rabbit mAb (PBS Only)

db11892-PBS

Datasheet

Product Name : Phospho-TAK1 (Ser439) (DGR20443) Rabbit mAb (PBS Only)

Cat.No.: db11892-PBS

Synonyms : CSCF; FMD2; TAK1; MEKK7; TGF1a

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser439 of human TAK1
Gene ID 6885
Swiss Prot O43318
Synonyms CSCF; FMD2; TAK1; MEKK7; TGF1a
Reactivity Human,Mouse,Rat
Application WB, IP
Recommended dilution WB: 1:1000-1:5000
IP: 1:10-1:100
Calculated MW 67 kDa
Observed MW 78 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20443
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Western blot detection of TAK1 (Phospho-Ser439) in 3T3,C6,MCF7 cell lysates using db11892(1:1000 diluted).
Western blot analysis of extracts from SCC-9 cells using db11892

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