ERK2 (DGR13303) Rabbit mAb (PBS Only)
Product Name :
ERK2 (DGR13303) Rabbit mAb (PBS Only)
Cat.No.:
db11918-PBS
Synonyms :
ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
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Background
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
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Immunogen
A synthetic peptide of human ERK2
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Gene ID
5594
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Swiss Prot
P28482
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Synonyms
ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC: 1:100
ICC/IF: 1:200-1:2000
FC: 1:200-1:1000
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Calculated MW
41 kDa
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Observed MW
41 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR13303
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
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Western blot detection of p42 MAPK (ERK2) in K562,Rat Brain,C6,3T3,Hela cell lysates using
db11918(1:1000 diluted).
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Western blot analysis of extracts from Jurkat,HCT116 cells using
db11918
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.