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ERK2 (DGR13303) Rabbit mAb (PBS Only)
db11918-PBS
Datasheet

Product Name : ERK2 (DGR13303) Rabbit mAb (PBS Only)

Cat.No.: db11918-PBS

Synonyms : ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
  • Immunogen A synthetic peptide of human ERK2
  • Gene ID 5594
  • Swiss Prot P28482
  • Synonyms ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC
  • Recommended dilution WB: 1:1000
    IHC: 1:100
    ICC/IF: 1:200-1:2000
    FC: 1:200-1:1000
  • Calculated MW 41 kDa
  • Observed MW 41 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR13303
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/ml
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot detection of p42 MAPK (ERK2) in K562,Rat Brain,C6,3T3,Hela cell lysates using db11918(1:1000 diluted).
  • Western blot analysis of extracts from Jurkat,HCT116 cells using db11918
订购信息
  • Package Price (RMB)
  • 100μg 5798
  • 货期:现货
For research use only. Not intended for diagnostic.