Collagen I单克隆抗体(DGR32808) | 高特异性&高亲和力

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Recombinant DGRmAb^®

Collagen I (DGR32808) Rabbit mAb (PBS Only)

db11923-PBS

Datasheet

Product Name : Collagen I (DGR32808) Rabbit mAb (PBS Only)

Cat.No.: db11923-PBS

Synonyms : OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Immunogen Recombinant protein of human Collagen I
Gene ID 1277
1278
Swiss Prot P02452
P08123
Synonyms OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1
Reactivity Human,Mouse,Rat
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20-1:50
Calculated MW 139 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR32808
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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