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HDAC1 (DGR13518) Rabbit mAb (AF488)
db11944-DL488
Datasheet
Conjugation/Formulation：AF488
- Background Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human HDAC1
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Gene ID
3065
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Swiss Prot
Q13547
- Synonyms HD1; RPD3; GON-10; RPD3L1
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC, IP
- Recommended dilution ICC/IF: 1:200
- Calculated MW 55 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13518
- Isotype IgG
- Purity Affinity Purification
- Conjugation AF488
- Concentration 1 mg/mL
- Storage/Stability Store at -20°C. Avoid exposure to light. Supplied in PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. Stable for 12 months from date of receipt.
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Immunofluorescence analysis of HeLa cells labelling HDAC1 with db11944-DL488.
The cells were fixed with 4% PFA (10min, RT) followed by treatment with 0.1% Triton X-100 (10min, RT), and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with db11944-DL488 (1:200, shown in green) at room temprature for 1h. Nuclear DNA was labeled in blue with DAPI.
Control: DAPI only.
订购信息
- Package Price (RMB)
- 100μL 2698
- 货期：现货
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For research use only. Not intended for diagnostic.
