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SERCA2 ATPase (DGR18385) Rabbit mAb
db12002
Datasheet
- Background This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]
- Immunogen A synthetic peptide of human SERCA2 ATPase
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Gene ID
488
-
Swiss Prot
P16615
- Synonyms DD; DAR; ATP2B; SERCA2
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50-1:100
ICC/IF: 1:100-1:200
FC: 1:100-1:1000 - Calculated MW 115 kDa
- Observed MW 115 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR18385
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of SERCA2 ATPase in K562,Hela cell lysates using SERCA2 ATPase antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human colon cancer using db12002 antibody. -
Immunofluorescent analysis of HeLa cells using db12002 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
