TPMT (DGR33330) Rabbit mAb (PBS Only)
Product Name :
TPMT (DGR33330) Rabbit mAb (PBS Only)
Cat.No.:
db12003-PBS
Synonyms :
TPMTD
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:PBS Only
-
Background
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014]
-
Immunogen
A synthetic peptide of human TPMT
-
Gene ID
7172
-
Swiss Prot
P51580
-
Synonyms
TPMTD
-
Reactivity
Human,Mouse,Rat
-
Application
WB, IHC-P, FC
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
FC: 1:100-1:500
-
Calculated MW
28 kDa
-
Observed MW
28 kDa
-
Host species
Rabbit
-
Clonality
Monoclonal
-
Clonality No.
DGR33330
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Concentration
1 mg/ml
-
Formulation
PBS Only
-
Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
-
Western blot detection of TPMT in Hela,A549,HL-60 cell lysates using
db12003(1:1000 diluted).
-
Immunohistochemical analysis of paraffin-embedded human Cholangiocarcinoma using
db12003
订购信息
-
Package
Price (RMB)
-
100μg
5798
- 货期:现货
For research use only. Not intended for diagnostic.