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TPMT (DGR33330) Rabbit mAb (PBS Only)
db12003-PBS
Datasheet

Product Name : TPMT (DGR33330) Rabbit mAb (PBS Only)

Cat.No.: db12003-PBS

Synonyms : TPMTD

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014]
  • Immunogen A synthetic peptide of human TPMT
  • Gene ID 7172
  • Swiss Prot P51580
  • Synonyms TPMTD
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P, FC
  • Recommended dilution WB: 1:1000-1:5000
    IHC-P: 1:100-1:200
    FC: 1:100-1:500
  • Calculated MW 28 kDa
  • Observed MW 28 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR33330
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/ml
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot detection of TPMT in Hela,A549,HL-60 cell lysates using db12003(1:1000 diluted).
  • Immunohistochemical analysis of paraffin-embedded human Cholangiocarcinoma using db12003
订购信息
  • Package Price (RMB)
  • 100μg 5798
  • 货期:现货
For research use only. Not intended for diagnostic.