您当前的位置：
Metabotropic Glutamate Receptor 2 (DGR18389) Rabbit mAb (PBS Only)
db12007-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
- Immunogen A synthetic peptide of human Metabotropic Glutamate Receptor 2
-
Gene ID
2912
-
Swiss Prot
Q14416
- Synonyms GLUR2; mGlu2; GPRC1B; MGLUR2
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC
-
Recommended dilution
WB: 1:2000-1:20000
IHC-P: 1:200-1:2000
ICC/IF: 1:200-1:500
FC: 1:50-1:100 - Calculated MW 99 kDa
- Observed MW 99 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR18389
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
![]()
-
Western blot detection of Metabotropic Glutamate Receptor 2 in K562,Hela cell lysates using Metabotropic Glutamate Receptor 2 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded mouse testis using db12007
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
