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PMCA1 (DGR14854) Rabbit mAb
db12009
Datasheet
- Background The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human PMCA1
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Gene ID
490
-
Swiss Prot
P20020
- Synonyms PMCA1; PMCA1kb
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, IP
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
IP: 1:20-1:50 - Calculated MW 139 kDa
- Observed MW 130-250 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14854
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from T24 cells using db12009 at 1:2000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
