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PRNP (DGR16827) Rabbit mAb (PBS Only)
db12127-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
- Immunogen A synthetic peptide of human PRNP
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Gene ID
5621
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Swiss Prot
P04156
- Synonyms CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, FC
- Calculated MW 28 kDa
- Observed MW 28 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16827
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Immunohistochemical analysis of paraffin-embedded human breast cancer using db12127 antibody. -
Western blot analysis of extracts from Rat brain tissue using db12127 at 1:1000. -
Western blot analysis of extracts from Mouse brain tissue using db12127 at 1:1000. -
Western blot analysis of extracts from U251 cells using db12127 at 1:1000.
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
