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Caspase-11 (DGR21042) Rabbit mAb (PBS Only)
db12404-PBS
Datasheet
Product Name : Caspase-11 (DGR21042) Rabbit mAb (PBS Only)
Cat.No.: db12404-PBS
Synonyms : Caspl; ich-3; CASP-4; Casp11; CASP-11
Application：
Reactivity : Mouse
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]
- Immunogen Recombinant protein of mouse Caspase-11
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Gene ID
12363
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Swiss Prot
P70343
- Synonyms Caspl; ich-3; CASP-4; Casp11; CASP-11
- Reactivity Mouse
- Application WB
- Calculated MW 43 kDa
- Observed MW 43 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR21042
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from RAW264.7 cells using db12404 at 1:1000.
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
