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Product Name : alpha 2 Macroglobulin (DGR34720) Rabbit mAb
Cat.No.: db12430
Synonyms : A2MD; CPAMD5; FWP007; S863-7
Application：
Reactivity : Human
Host species : Rabbit
Conjugation/Formulation：Un-conjugated
- Background The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
- Immunogen A synthetic peptide of human alpha 2 Macroglobulin
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Gene ID
2
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Swiss Prot
P01023
- Synonyms A2MD; CPAMD5; FWP007; S863-7
- Reactivity Human
- Application WB
- Recommended dilution WB: 1:1000-1:5000
- Calculated MW 163 kDa
- Observed MW 163 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR34720
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Human plasma tissue using db12430 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
