HIF-1-alpha单克隆抗体(DGR11905) | 高特异性&高亲和力

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Recombinant DGRmAb^®

HIF-1-alpha (DGR11905) Rabbit mAb (PBS Only)

db12445-PBS

Datasheet

Product Name : HIF-1-alpha (DGR11905) Rabbit mAb (PBS Only)

Cat.No.: db12445-PBS

Synonyms : HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated PBS Only

Background This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Immunogen Recombinant protein of human HIF-1-alpha
Gene ID 3091
Swiss Prot Q16665
Synonyms HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha
Reactivity Human,Mouse,Rat
Application WB, ICC/IF, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:200-1:500
IP: 1:20-1:50
Calculated MW 92 kDa
Observed MW 120 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR11905
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/ml
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

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