CD35 (DGR19579) Rabbit mAb (PBS Only)
Product Name :
CD35 (DGR19579) Rabbit mAb (PBS Only)
Cat.No.:
db12493-PBS
Synonyms :
KN; C3BR; C4BR; CD35
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human CD35
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Gene ID
1378
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Swiss Prot
P17927
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Synonyms
KN; C3BR; C4BR; CD35
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Reactivity
Human
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
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Calculated MW
224 kDa
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Observed MW
280 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR19579
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/ml
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
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