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CD146 (DGR13821) Rabbit mAb (PBS Only)
db12516-PBS
Datasheet

Product Name : CD146 (DGR13821) Rabbit mAb (PBS Only)

Cat.No.: db12516-PBS

Synonyms : CD146; MUC18

Application:

Reactivity : Human

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
  • Immunogen A synthetic peptide of human CD146
  • Gene ID 4162
  • Swiss Prot P43121
  • Synonyms CD146; MUC18
  • Reactivity Human
  • Application WB
  • Calculated MW 72 kDa
  • Observed MW 120 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR13821
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from A375 cells using db12516 at 1:1000.
订购信息
  • Package Price (RMB)
  • 100μg 4498
  • 货期:现货
For research use only. Not intended for diagnostic.