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Phospho-PKC (Ser660) (DGR33934) Rabbit mAb (PBS Only)
db12603-PBS
Datasheet

Product Name : Phospho-PKC (Ser660) (DGR33934) Rabbit mAb (PBS Only)

Cat.No.: db12603-PBS

Synonyms : AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser660 of human PKC
  • Gene ID 5578
    5579
    5580
    5581
    5583
    5588
  • Swiss Prot P17252
    P05771
    P05771-2
    Q05655
    Q02156
    P24723
    Q04759
  • Synonyms AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha
  • Reactivity Human,Mouse,Rat
  • Application WB, IHC-P
  • Calculated MW 78 kDa
  • Observed MW 78-85 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR33934
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Immunohistochemical analysis of paraffin-embedded human Brain using db12603 antibody.
  • Western blot analysis of extracts from HeLa, A549, HL-60, U2OS, C6 cells using db12603 at 1:1000.
订购信息
  • Package Price (RMB)
  • 100μg 5798
  • 货期:现货
For research use only. Not intended for diagnostic.