Phospho-Bad (Ser112) (DGR32836) Rabbit mAb (PBS Only)
Product Name :
Phospho-Bad (Ser112) (DGR32836) Rabbit mAb (PBS Only)
Cat.No.:
db12648-PBS
Synonyms :
BBC2; BCL2L8
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation：PBS Only
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Background
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser112 of human Bad
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Gene ID
572
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Swiss Prot
Q92934
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Synonyms
BBC2; BCL2L8
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Reactivity
Human,Mouse,Rat
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Application
WB, IP
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Calculated MW
18 kDa
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Observed MW
23 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR32836
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Concentration
1 mg/mL
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Formulation
PBS Only
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Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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100μg
4498
- 货期：现货
For research use only. Not intended for diagnostic.
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