Phospho-beta Catenin (Thr41/Ser45) (DGR32131) Rabbit mAb (PBS Only)
Product Name :
Phospho-beta Catenin (Thr41/Ser45) (DGR32131) Rabbit mAb (PBS Only)
Cat.No.:
db12676-PBS
Synonyms :
EVR7; CTNNB; MRD19; NEDSDV; armadillo
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：PBS Only
-
Background
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
-
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Thr41/Ser45 of human beta Catenin
-
Gene ID
1499
-
Swiss Prot
P35222
-
Synonyms
EVR7; CTNNB; MRD19; NEDSDV; armadillo
-
Reactivity
Human
-
Application
WB
-
Calculated MW
86 kDa
-
Observed MW
86 kDa
-
Host species
Rabbit
-
Clonality
Monoclonal
-
Clonality No.
DGR32131
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Concentration
1 mg/ml
-
Formulation
PBS Only
-
Storage/Stability
Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
100μg
5798
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号