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Caspase-10 (DGR14068) Rabbit mAb (PBS Only)
db12792-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
- Immunogen Recombinant protein of human Caspase-10
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Gene ID
843
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Swiss Prot
Q92851
- Synonyms MCH4; ALPS2; FLICE2
- Reactivity Human
- Application WB, IHC-P, FC, IP
- Calculated MW 59 kDa
- Observed MW 59 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14068
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of Caspase 10 in K562 cell lysates using Caspase 10 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human lung cancer using db12792 antibody.
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
