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DR5 (DGR18370) Rabbit mAb (PBS Only)
db12888-PBS
Datasheet

Product Name : DR5 (DGR18370) Rabbit mAb (PBS Only)

Cat.No.: db12888-PBS

Synonyms : DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5

Application:

Reactivity : Human

Host species : Rabbit

Conjugation/Formulation:PBS Only

  • Background The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
  • Immunogen A synthetic peptide of human DR5
  • Gene ID 8795
  • Swiss Prot O14763
  • Synonyms DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
  • Reactivity Human
  • Application WB, IHC-P, IP
  • Calculated MW 49 kDa
  • Observed MW 40,49 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR18370
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from HT-1080 cells using db12888 at 1:1000.
订购信息
  • Package Price (RMB)
  • 100μg 5798
  • 货期:现货
For research use only. Not intended for diagnostic.