您当前的位置：
PEN2 (DGR32344) Rabbit mAb (PBS Only)
db12942-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Immunogen A synthetic peptide of human PEN2
-
Gene ID
55851
-
Swiss Prot
Q9NZ42
- Synonyms PEN2; PEN-2; MDS033; ACNINV2; MSTP064
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, FC
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
FC: 1:100-1:500 - Calculated MW 12 kDa
- Observed MW 12 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR32344
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
×
![]()
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
