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ROCK1 (DGR15339) Rabbit mAb (PBS Only)
db13063-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]
- Immunogen A synthetic peptide of human ROCK1
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Gene ID
6093
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Swiss Prot
Q13464
- Synonyms ROCK-I; P160ROCK
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, FC, IP
- Calculated MW 158 kDa
- Observed MW 158 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15339
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of ROCK1 in C6,3T3,Hela cell lysates using ROCK1 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 100μg 4498
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
