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Conjugation/Formulation：Un-conjugated
- Background HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human HLA DMB
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Gene ID
3109
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Swiss Prot
P28068
- Synonyms RING7; D6S221E
- Reactivity Human
- Application WB, IHC-P, ICC/IF
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
ICC/IF: 1:100-1:500 - Calculated MW 29 kDa
- Observed MW 29 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR33579
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Raji cells using db13103 at 1:1000.
订购信息
- Package Price (RMB)
- 10μL 398
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
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For research use only. Not intended for diagnostic.
