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Cellular Apoptosis Susceptibility (DGR15599) Rabbit mAb (PBS Only)
db13105-PBS
Datasheet
Conjugation/Formulation：PBS Only
- Background Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
- Immunogen A synthetic peptide of human Cellular Apoptosis Susceptibility
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Gene ID
1434
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Swiss Prot
P55060
- Synonyms CAS; CSE1; XPO2
- Reactivity Human,Mouse
- Application WB, IHC-P, ICC/IF
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50-1:100
ICC/IF: 1:200-1:500 - Calculated MW 110 kDa
- Observed MW 110 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR15599
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/ml
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Western blot detection of Cellular Apoptosis Susceptibility in 3T3,Hela cell lysates using db13105(1:1000 diluted).
订购信息
- Package Price (RMB)
- 100μg 5798
- 货期：现货
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For research use only. Not intended for diagnostic.
